prosthetic valve endocarditis การใช้

• Daptomycin has not been studied in patients with prosthetic valve endocarditis or meningitis.
• It is an opportunistic pathogen that can cause bacteremia, meningitis, prosthetic valve endocarditis, peritonitis in humans and animals.
• Prosthetic valve endocarditis is commonly caused by " Staphylococcus epidermidis " as it is capable of growing as a biofilm on plastic surfaces.
• This short introduction may help to reflect on the various and sometimes opposing view-points concerning the'origin'of prosthetic valve endocarditis.
• "Prosthetic valve endocarditis arising within two months of valve surgery is generally the result of intra-operative contamination of the prosthesis or a bacteraemic post-operative complication.
• CoNS species, such as " S . epidermidis " and " S . capitis ", are recorded as the most common cause of prosthetic valve endocarditis.
• "Epidemiologic evidence suggests that prosthetic valve endocarditis due to coagulase negative staphylococci that presents between 2 and 12 months after surgery is often nosocomial in origin but with a delayed onset ."
• The cumulative rate of prosthetic valve endocarditis is 1.5 to 3.0 % at one year following valve replacement and 3 to 6 % at five years, the risk being the greatest during the first six months after valve replacement.
• ""'Legionella dumoffii " "'is a Gram-negative bacterium from the genus " Legionella " with a monopolar flagellum which was isolated from lung tissue of a patient who suffered from fatal pneumonia . " L . dumoffii " occurs in soil and freshwater environments and can cause human pneumonia and accidentally induce other diseases such as prosthetic valve endocarditis and septic arthritis.